SKIN1004 Centella vs. SKIN1004 Probio-Cica
The brand's own site is direct about this one: not a simple swap. A single-ingredient centella ampoule against a fermented, ceramide-boosted intensive formula.
Criteria | SKIN1004 Madagascar Centella Ampoule | SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule |
|---|---|---|
| Price | $22.00 | $24.00 |
| Price / unit | $0.22/mL | $0.48/mL |
| Size | 100 mL | 50 mL |
| Price checked | 9/12/2026 | 9/16/2026 |
Both come from the same brand and share centella as a headline ingredient, but SKIN1004's own product data is explicit: these solve different problems, not the same one at two price points.
Why compare these two specifically
Same brand, same headline botanical, genuinely different formulas. Worth clarifying directly which one actually fits a given need, rather than assuming the pricier option is simply 'more' of the same thing.
Price per milliliter
SKIN1004 Centella Ampoule runs $0.22 per milliliter ($22.00 for 100mL). SKIN1004 Probio-Cica runs $0.48 per milliliter ($24.00 for 50mL). Probio-Cica costs more than double per mL, in a bottle half the size.
Single-ingredient purity vs. fermented, barrier-focused formula
The plain Centella Ampoule is built around Madagascar-sourced centella asiatica alone, nothing else highlighted. Probio-Cica uses fermented centella specifically, alongside niacinamide, real Ceramide NP, and madecassoside, a genuinely more intensive, barrier-focused formula built for a different job.
The brand itself flags this distinction
SKIN1004 positions Probio-Cica as more intensive and barrier-focused than the plain Centella Ampoule, worth choosing based on which specific need you have rather than treating it as a simple upgrade.
Our take
If you want the purest, lowest-risk, lowest-cost centella option, the plain Ampoule remains the right pick, and there's no reason to pay double for Probio-Cica if barrier support isn't a specific concern. If your skin needs real barrier reinforcement alongside centella, ceramide NP and the fermented formulation genuinely justify Probio-Cica's premium.
SKIN1004 Madagascar Centella Ampoule: $0.22/mL. A single-ingredient, fragrance-free centella formula, the purest and lowest-cost option in the line.
SKIN1004 Madagascar Centella Probio-Cica Intensive Ampoule: $0.48/mL. Fermented centella plus real Ceramide NP, a more intensive, barrier-focused formula for a specific need, not a simple upgrade.
See our full best Korean serums by concern guide, or browse the rest of our serum coverage.
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Price checked 9/12/2026
Price checked 9/16/2026
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Frequently asked
What's the difference between SKIN1004 Centella Ampoule and Probio-Cica?
The plain Centella Ampoule is a single-ingredient formula, Madagascar centella asiatica alone. Probio-Cica uses fermented centella alongside niacinamide, real Ceramide NP, and madecassoside, a more intensive, barrier-focused formula, not a simple upgrade of the original.
Is SKIN1004 Probio-Cica better than the plain Centella Ampoule?
Not universally, they're built for different needs. The brand itself positions Probio-Cica as more intensive and barrier-focused, worth choosing based on whether you actually need that, not just as an upgrade.
Which is cheaper, SKIN1004 Centella Ampoule or Probio-Cica?
The plain Centella Ampoule, at $0.22 per milliliter versus Probio-Cica's $0.48 per milliliter, less than half the cost.