medicube TXA Niacinamide Serum
By Nur → Last verified 10/5/2026
Price checked 10/5/2026
Verified 2026-10-05 on the brand's US store: $24.00 (list $26.00; Sale ($24 ~~$26~~ on brand search tile)). Prices change often, so confirm on the retailer's page.
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What we found
Based on how this product compares to others in the serums category, cross-referenced against retailer listings and market data.
Strengths
- + Contains alpha-arbutin, tranexamic acid, niacinamide, glutathione and sodium hyaluronate
Worth knowing
- - Not fragrance-free: the ingredient list includes essential oils (Rosa Centifolia Flower Oil)
- - Some retailers title it TXA Niacinamide 15 Serum; the ingredient list is the US version, copied from the Ulta page
- - The brand describes the formula as fragrance-free, but the ingredient list includes rose flower oil
Key ingredients
These are the ingredients medicube highlights for this product, cross-checked against general dermatological and cosmetic-chemistry sources, not a full INCI list.
Fragrance: The ingredient list includes essential oils, so it is not fragrance-free.
| Ingredient | What it is | What it does for skin |
|---|---|---|
| Alpha-arbutin | A stable, skin-brightening compound derived from the bearberry plant and also made synthetically. | Slows pigment production in skin cells, helping fade the look of dark spots and uneven tone over weeks.Note: Works gradually and should be paired with daily sunscreen. |
| Tranexamic acid | A synthetic amino-acid derivative used medically to reduce bleeding and in skincare for uneven tone. | Used in cosmetics for brightening and to help fade the look of dark spots; results at skincare strengths are modest and build slowly. |
| Niacinamide | A form of vitamin B3, one of the most studied ingredients in cosmetic dermatology. | Strengthens the skin barrier by boosting ceramide production, helps even out tone by limiting pigment transfer to skin cells, and can reduce the look of enlarged pores. |
| Glutathione | An antioxidant naturally produced by the body, also used topically in some brightening formulas. | Helps neutralize free radicals and is marketed for brightening, though topical absorption and efficacy are less established than oral or injectable use. |
| Sodium hyaluronate | The salt form of hyaluronic acid, commonly used for its water solubility and stability in formulas; molecular weight varies by product rather than being uniformly smaller. | Draws and holds moisture the same way hyaluronic acid does; how easily it absorbs depends on the specific molecular weight used, which formulas don't always disclose. |
| Hydrolyzed hyaluronic acid | Hyaluronic acid broken into smaller fragments. | A humectant that holds water at the skin surface; the smaller size is meant to hydrate at a shallower depth. |
What the brand says
medicube's own marketing claims, not our own findings.
- 72-hour serum for dark spots, acne scars, uneven tone and texture
- 10-layer hyaluronic acid, panthenol and betaine
- 5% tranexamic acid, medicube's highest TXA concentration
- Blend of 5% tranexamic acid, 10% niacinamide and 2% arbutin
- Brand-reported 2.045% improvement in skin clarity and 18.1% in hydration after 72 hours (clinical trial)
Research-Based
Our assessment comes from pricing, ingredients, and published information, not personal use, the same standard we apply across the site. This product hasn't been hands-on tested yet. See our Methodology for what that distinction means.
Price history
Current price is the lowest we've recorded so far.
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Frequently asked
How much does medicube TXA Niacinamide Serum cost per mL?
$0.80 per mL (currently $24.00 for 30 mL).
Has medicube TXA Niacinamide Serum been hands-on tested?
Not yet. Our assessment for this product comes from pricing, ingredients, and published information, not personal use, the same standard we apply across the site. See our Methodology for what that distinction means.
What are the key ingredients in medicube TXA Niacinamide Serum?
The ingredients medicube highlights for this product include Alpha-arbutin, Tranexamic acid, Niacinamide, Glutathione, Sodium hyaluronate, Hydrolyzed hyaluronic acid.
Sources
Pricing and availability for this product were verified against the following retailer listings.