Madecassoside

By Nur → Last verified 9/26/2026

What it is

Madecassoside is one of centella asiatica's key active compounds, often isolated and purified from the whole plant extract and used in skincare at its own concentration, separate from or alongside centella asiatica itself.

What the evidence says

A soothing, antioxidant compound studied for calming sensitive and reactive skin and supporting barrier repair. It's frequently paired with centella asiatica in the same formula rather than used alone, since the two work as a soothing pairing. MEDIHEAL built an entire sunscreen around a brand-stated 98% pure madecassoside complex specifically.

Who it's for

Reactive, sensitive, or redness-prone skin specifically looking for a soothing-focused formula.

Worth knowing

No specific group needs to avoid it, it's broadly considered gentle and well-tolerated.

Where you'll find it

Products in our catalog that list Madecassoside as a key ingredient.

Frequently asked

What is madecassoside?

It's one of centella asiatica's key active compounds, often isolated and purified from the whole extract and used in skincare at its own disclosed concentration.

What does madecassoside do for skin?

It's a soothing, antioxidant compound studied for calming sensitive and reactive skin and supporting barrier repair.

Is madecassoside different from centella asiatica?

Madecassoside is a specific compound isolated from centella asiatica, not the whole plant extract. The two are frequently used together in the same formula.

Which products use a high concentration of madecassoside?

MEDIHEAL's Madecassoside Moisture Sun Serum is built around a brand-stated 98% pure madecassoside complex specifically.